This roundtable will explore the evolving regulatory landscape for artificial intelligence (AI) in healthcare, with a specific focus on Israel’s unique ecosystem. AI is increasingly being explored and integrated across various healthcare domains, including medical device development, clinical decision support tools, post-market surveillance, population health management, hospital operations, regulatory oversight, and quality control systems, to varying degrees and at different stages of maturity. The discussion will aim to move beyond experimentation and “sandbox” initiatives toward a practical dedicated Task Force that  will promote a structured and coordinated regulatory framework for Israel.